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Cellular reprogrammingRetro Biosciences—Cellular reprogrammingRetro Biosciences—Anti-aging drugsBioAge Labs—Anti-aging drugsCambrian Bio—Cellular reprogrammingNewLimit—Pet longevityLoyal—Anti-aging drugsCalico—Anti-aging drugsBioAge Labs—Cellular reprogrammingNewLimit—Pet longevityLoyal—Cellular reprogrammingNewLimit—Cellular reprogrammingNewLimit—Anti-aging drugsCalico—Institutes & fundersHevolution Foundation—Anti-aging drugsBioAge Labs—Anti-aging drugsBioAge Labs—Cellular reprogrammingRejuvenate Bio—Anti-aging drugsCambrian Bio—Anti-aging drugsBioAge Labs—Cellular reprogrammingLife Biosciences—
Fields

Longevity, four fields

15 programs11 companies0 updates this week

Longevity, fifteen programs

15 shown · 15 tracked
LOY-001 / LOY-003Lowering growth hormone, big dogsLoyalPilotRemaining FDA sections—24d ago
BGE-102 (NLRP3)Anti-inflammation pill, heart riskBioAge LabsProtoDose-finding trial in heart risk20262mo ago
Hepatocyte epigenetic reprogrammingMaking old liver cells young, mRNANewLimitResearchPre-trial studies and manufacturing—3mo ago
Fosigotifator (ABBV-CLS-7262)Pill that calms a cell stress alarmCalicoPilotFinish rare-disease trial—4mo ago
Pipeline companiesHub of aging biotechs, rapamycin-like drugsCambrian BioProtoPhase 2 trials of ATX-304 (REWIRE-1 and REWIRE-2)—4mo ago
ER-100Eye injection of reprogramming genesLife BiosciencesProtoTrial fully enrolled (up to 18)—4mo ago
T cell rejuvenationMaking old immune cells youngNewLimitResearchPick lead candidate—7mo ago
LOY-002Daily pill for senior dogsLoyalDeployManufacturing section accepted—8mo ago
PAI-1 inhibitorPill for scarring and metabolic diseaseJuvenescenceProtoPhase 2 starts20269mo ago
Healthspan grants and summitGrants, startup investing, summitsHevolution FoundationScaling—10mo ago
RTR242 (autophagy)Pill to restart cell cleanup, Alzheimer'sRetro BiosciencesProtoFinish safety trial—10mo ago
Cellular rejuvenation programmingPartial reprogramming, reversing diseaseAltos LabsResearchPick first drug for trials—10mo ago
OSK partial reprogramming gene therapyReprogramming genes delivered by virusRejuvenate BioResearchBig-animal and disease studies—3y ago
Canine mitral valve disease gene therapyGene therapy for a dog heart-valve diseaseRejuvenate BioPilotVet study of whether it works—4y ago
Blood and microglia replacementYoung lab-made blood and brain cellsRetro BiosciencesResearchStudies needed before trials——
Target is the next milestone’s date; +N mo marks a slip against the original target
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