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TheTechno Optimist.

mRNA medicinesModerna—Gene editingCRISPR Therapeutics—Gene editingIntellia Therapeutics—AI drug discoveryGenerate Biomedicines—Obesity & metabolismNovo Nordisk—AI drug discoveryIsomorphic Labs—Obesity & metabolismEli Lilly—Pivot Bio—Gene editingPrime Medicine—AI drug discoveryGenerate Biomedicines—Obesity & metabolismEli Lilly—Obesity & metabolismEli Lilly—Gene editingIntellia Therapeutics—AI drug discoveryRecursion—Gene editingIntellia Therapeutics—Obesity & metabolismEli Lilly—Obesity & metabolismNovo Nordisk—Obesity & metabolismEli Lilly—Obesity & metabolismEli Lilly—De-extinctionColossal Biosciences—
Fields

Biotech, six fields

24 programs14 companies0 updates this week

Biotech, 24 programs

24 shown · 24 tracked
Orforglipron (Foundayo)Daily GLP-1 pill for obesityEli LillyScalingUS launch; diabetes filing—25d ago
RetatrutideThree-hormone weekly shotEli LillyDeployFiling for obesity approval—25d ago
Lonvo-z (NTLA-2002)In-body CRISPR for hereditary angioedemaIntellia TherapeuticsDeployUS commercial launch202732d ago
BEAM-302 (AATD)In-body base editing, fixes AATD typoBeam TherapeuticsPilotFinish key group for a fast-track FDA filing—32d ago
Tirzepatide (Mounjaro / Zepbound)Weekly shot, two-hormone GLP-1 drugEli LillyScalingHeart-outcome results and new uses—43d ago
CTX310 (ANGPTL3)In-body CRISPR, lowers blood fatsCRISPR TherapeuticsProtoNext trial in very high blood fats or cholesterol—43d ago
Intismeran autogene (mRNA-4157/V940)Personal mRNA cancer vaccine, melanomaModernaDeployFiling with regulators—2mo ago
Nex-z (NTLA-2001)In-body CRISPR for ATTR amyloidosisIntellia TherapeuticsDeployFinish enrolling and following the Phase 3—2mo ago
Recursion OS and pipelineCell-image maps, AI supercomputer, trialsRecursionProtoShow trial results from AI-found drugs—2mo ago
PM577a (Wilson disease)In-body prime editing, Wilson diseasePrime MedicineResearchFirst patient dosed20263mo ago
PM359 (CGD)Prime-edited stem cells, immune disorderPrime MedicineProto—4mo ago
VERVE-102 (PCSK9 base editor)One-time base edit to lower cholesterolEli LillyProtoLarger dosing and Phase 2 plans—5mo ago
Risto-cel (BEAM-101)Base-edited stem cells for sickle cellBeam TherapeuticsPilotFDA filingQ4 20265mo ago
Wegovy (semaglutide)GLP-1 weekly shot and daily pillNovo NordiskScaling—7mo ago
Drug design engine and pipelineAI-designed drugs for cancer and immunityIsomorphic LabsResearchFirst AI-designed drug in clinical trials+12 moDec 20268mo ago
GB-0895 (anti-TSLP)Long-lasting antibody for severe asthmaGenerate BiomedicinesDeployPhase 3 fully enrolled (~1,600 patients)20289mo ago
CagriSemaTwo-hormone weekly shotNovo NordiskDeployFDA decision20261y ago
Dire wolfEdited gray wolf, cloningColossal BiosciencesProto—2y ago
Woolly mammothCold-adapted elephant with mammoth traitsColossal BiosciencesResearchEdited elephant embryos and a pregnancy—2y ago
Evo genomic foundation modelsDNA language models, openArc InstitutePilotExtend design to complex (eukaryotic) genomes—2y ago
Respiratory vaccinesCOVID and RSV mRNA vaccinesModernaScaling—2y ago
Casgevy (exa-cel)CRISPR cure for sickle cellCRISPR TherapeuticsScalingMore treatment centers, more patients—3y ago
Ginkgo Automation and DatapointsModular lab robots, biology dataGinkgo BioworksDeploy—4y ago
ML-driven target discoveryLab-grown cells, genetics, AIinsitroResearchFirst own drug into trials—6y ago
Target is the next milestone’s date; +N mo marks a slip against the original target
Primer