Nature: team identifies the spinal neurons that stimulation recruits to restore walking

ONWARD Medical/ARC Therapy (ARC-EX / ARC-IM / ARC-BCI)

Epidural stimulation during rehab restored walking in nine people with chronic spinal cord injury. Mouse experiments with single-nucleus RNA sequencing pinpointed one population of excitatory spinal interneurons that the therapy recruits and that is needed for recovery.

• Nine people with chronic spinal cord injury regained walking with epidural stimulation
• Researchers identified specific excitatory spinal interneuron population required for recovery
• Mouse studies confirmed this neuron population is necessary for therapeutic effect
• Published in Nature identifying the neural mechanism of spinal stimulation therapy