The brief
- VK2735 phase 3 VANQUISH trials fully enrolled with ~5,600 patients in obesity and obesity+diabetes cohorts.
- Phase 2 (VENTURE) showed up to 14.7% weight reduction in 13 weeks, dose-dependent.
- Viking is the first to advance both weekly SC and daily oral formulations of a GLP-1/GIP dual into phase 3.
Technical approach
Dual agonism
GLP-1 and GIP receptor activation
VK2735 activates both GLP-1 (appetite suppression) and GIP (metabolic benefits). Combination maximizes weight loss.
Formulation flexibility
SC injection and oral tablet
Viking develops weekly SC and daily oral forms, giving patients choice and improving compliance.
Dosing strategy
Long-acting depot
Weekly SC dosing reduces injection frequency versus daily oral or twice-weekly competitors.
