The brief

Analyst view

• TelemedicineRx across all 50 states prescribes compounds (rapamycin, metformin) studied for aging.
• PEARL trial (48 weeks, 114 adults, 50–85 yrs) found low-dose rapamycin safe; muscle and pain gains.
• XPRIZE Healthspan Milestone 2 ($1M, 2026–2029): trial of ~186 adults (50–90 yrs) on muscle, cognition, immune.

Technical approach

As reported

Drug Selection

Proven compounds, not novel drugs

Prescribes compounds studied in aging (rapamycin, metformin, semaglutide) vs inventing new therapies.

Remote Delivery

Telemedicine across all US states

The platform connects patients with doctors who evaluate and prescribe based on a remote intake, eliminating geography as a barrier.

Trial Design

Decentralized clinical research

PEARL enrolled US participants at home, collecting data remotely; longest rapamycin safety trial.