The brief

Analyst view

• Founded in March 2020 by Ryan Smith and Hannah Went, TruDiagnostic operates one of the world's largest DNA methylation databases.
• In March 2025, L'Oreal announced a strategic R&D partnership to study how epigenetics governs skin and hair aging.
• TruAge is used by 30+ clinical research teams and collaborates with 80+ academic partners.

Technical approach

As reported

Methylation clocks

Three biological age measures

TruAge reports DunedinPACE (aging speed), OMICmAge (age from 900k DNA sites), and SYMPHONYAge, validated against each other.

Organ systems

Aging across 11 body systems

TruAge measures aging in the brain, heart, liver, lungs, kidneys, pancreas, immune system and other organs, showing whether some age faster than others.

Database

6+ trillion data points

TruDiagnostic built one of the world's largest DNA methylation databases, measuring 1+ million sites per test, allowing age clocks to be improved.