The brief

Analyst view

• ARPA-H selected Stanford in Feb 2026 to develop biomarkers for healthspan across seven research teams.
• PROSPR-IC creates the first FDA-grade Intrinsic Capacity score to forecast health outcomes up to 20 years.
• Stanford will validate the score in a one-year lifestyle intervention trial with digital health monitoring.

Technical approach

As reported

Data harmonization

Combining existing datasets

PROSPR-IC integrates health records and biomarker measurements from multiple institutions into one unified database.

Composite scoring

Intrinsic Capacity score

Biomarkers of physical, cognitive, mental and social health are combined into one score predicting long-term health trajectory and remaining healthy life.

In-home monitoring

Digital health technology

Stanford is developing digital health tools for home use to track physical activity, sleep, cognitive function and other markers during the intervention trial.