MIT researchers release Boltz-1, first fully open-source model for biomolecular structure prediction at AlphaFold3-level accuracy

Boltz/Boltz-2 / BoltzGen open models

Researchers at MIT, led by Gabriele Corso and Jeremy Wohlwend, released Boltz-1, an open-source model for predicting 3D structures of biomolecular complexes. Distributed under the MIT license, Boltz-1 achieves accuracy comparable to proprietary AlphaFold3, democratizing access to structure prediction for academic and commercial use.