Demis Hassabis and John Jumper share the Nobel Prize in Chemistry for AlphaFold protein structure prediction

Isomorphic Labs/AlphaFold 3

Demis Hassabis and John Jumper of Google DeepMind shared half of the 2024 Nobel Prize in Chemistry for protein structure prediction with AlphaFold, which predicts a protein's 3D shape from its amino-acid sequence. The other half went to David Baker for computational protein design.

• AlphaFold solved a decades-long challenge: predicting 3D protein structures from sequences alone, accelerating drug discovery.
• AlphaFold's 50-year leap in accuracy to near-experimental precision transformed structural biology.
• Isomorphic Labs, co-founded by Hassabis, applies AlphaFold to drug discovery; David Baker's work enabled entirely new proteins to be designed.
• The prize recognizes both fundamental science and practical therapeutics impact.