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Interventions Testing Program (ITP)

by National Institute on Aging (NIA)US

Identify safe, orally-administered compounds that reliably extend healthy lifespan in mice, as a foundation for human longevity research.

DeployStage 4 of 5

The standard federal test for lifespan-extending compounds, accepting proposals for 2027 cohort.

Updated 2016Checked 11 Oct0 updates this week

Milestones

Next · Annual cohort proposals cycle
  1. ITP established1999Complete.
  2. Rapamycin shown to extend lifespan in mice2009Complete.
  3. Acarbose shown to extend lifespan2013Complete.
  4. 17α-estradiol shown to extend lifespan2016Complete.
  5. Annual cohort proposals cycleTarget 2026Current milestone.

Most important updates

Upcoming

  1. 2026Annual cohort proposals cycle (next)
  2. Q4 2026ITP 2027 proposal submissions and review
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