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Pairwise

CRISPR crops, seedless blackberry, Fulcrum platform

USprivateest. 2017pairwise.com (opens pairwise.com)Checked 25 Sep

The brief

Analyst view
  • Its milder mustard greens launched in 2023; it stopped marketing them in 2024 to focus on licensing and higher-value crops.
  • Unveiled the first seedless blackberry in June 2024; it cleared USDA review and heads to grower trials.
  • Builds its own editing tools, including base editors, so it doesn't depend on standard CRISPR licences.

Technical approach

As reported
Editing

Fulcrum platform

Its toolkit includes CRISPR and base editors, which change single DNA letters, to make precise edits with no foreign DNA left.

Traits

Switching off unwanted genes

Many edits just turn a gene off: the one that makes mustard greens pungent, or ones behind blackberry seeds and thorns.

Breeding

Skipping decades of breeding

Editing top varieties directly avoids long cross-breeding, which is especially slow in fruit plants that live for years.

Programs

Pairwise, two programs

Updated 1 Jan 2025
Research · Proto · Pilot · Deploy · Scaling

Research & demos

2 items

Open technical problems

Open · Active · Partial
  • Regulatory uncertaintyOpen

    A 2024 court ruling struck down USDA's SECURE rule, bringing back older rules; the EU, China and others differ too.

  • Will shoppers pay?Open

    Conscious Greens showed premium gene-edited produce struggles on shelves without a clear taste or price edge.

Peers

Gene-edited crops · 2

Company & funding

1 round · as reported
Raised
$90Mdisclosed private rounds
Last round
Series BJan 2021
HQ
US
Founded
2017
DateRoundAmountPost-moneyLead
Jan 2021Series B$90M—Deerfield Management

Partners & customers

2 partners · 1 investor

People

Key people
Primer