The brief

Analyst view

• Chromium platform leads single-cell genomics with 1 billion+ cells analyzed to date.
• Xenium spatial platform: 14,500 reactions in 2025 (+34% YoY); launched RNA+protein co-detection.
• Spatial consumables drove double-digit growth in 2025, entirely from Xenium expansion.

Technical approach

As reported

Microfluidics

Oil-water interface partitioning

Microfluidic droplets partition cells and barcoded gel beads, tagging millions of cells with unique molecular identifiers.

Single-cell RNA-seq

Chromium platform

Chromium (3' GEM, 5' GEM, multiome) profiles transcriptomes genome-wide in individual cells.

Spatial genomics

Xenium in-situ platform

Xenium multiplexes fluorescence in-situ hybridization (FISH) to map gene activity inside intact tissue sections.

Multimodal analysis

RNA and protein co-detection

Xenium Protein (August 2025) enables simultaneous RNA and protein measurement on the same tissue section.

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