BrainGate2 implant lets a man with ALS talk for a prolonged period, Nature Medicine reports

BrainGate consortium/BrainGate2 clinical trial (speech neuroprosthesis)

A 47-year-old man with ALS, Casey Harrell, used the BrainGate2 brain-computer interface to speak clearly and without assistance over a prolonged period. The results, from one participant, were published in Nature Medicine on 15 June 2026.

• Harrell rated 92% of sentences as accurate or mostly correct.
• In controlled tests with a 125,000-word vocabulary, the system scored over 99% word accuracy.
• The findings rest on a single participant; the trial is still enrolling.