# Profluent raises $106M Series B co-led by Altimeter and Bezos Expeditions

Canonical page: https://technooptimist.io/stories/profluent-raises-106m-series-b-co-led-by-altimeter-and-bezos-expeditions-6abacf7e
Date: 19 Nov 2025
About: [Profluent](https://technooptimist.io/companies/profluent.md)
Original source: https://www.bioxconomy.com/investment/profluent-raises-106m-to-advance-ai-driven-protein-design-platform

Profluent raised $106 million, bringing its total to $150 million, to scale its protein models and move beyond gene editing into antibodies, enzymes and other formats. The Emeryville, California company aims to put an AI-designed therapy into patients.

## Key facts

- Co-leads Altimeter Capital and Bezos Expeditions; Spark, Insight and Air Street also invested.
- Thousands of companies, labs and large pharma groups use OpenCRISPR-1, per the company.
- Partners include Revvity, Corteva, IDT and the Rett Syndrome Research Trust.

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